In view of this, this study analyzed the effect of NPS on 30-day all-cause mortality in 325 patients with APE at admission, and the results of the comparison revealed that patients with older age, faster heart rate, lower systolic blood pressure, low Alb and total cholesterol levels, high NLP, low LMR, right heart dilatation, heart failure, malignancy, and lower extremity venous thrombosis have higher 30-day all-cause mortality, and these differences were statistically significant (P < 0.05). This evidence concerns the gene ALB and apparent mineralocorticoid excess.