Another recent study also revealed that lncRNA, family with sequence similarity 225 member B (FAM225B) was found upregulated in NPC to promote cell proliferation and invasion via overexpression of integrin β3 (ITGB3) and activation of focal adhesion kinase (FAK)/PI3K/Akt pathways [194]. This evidence concerns the gene PIK3CA and nasopharyngeal carcinoma.