AKT1 and nasopharyngeal carcinoma: Briefly, LMP1-targeted DNAzymes were used to suppress the expression of LMP1; inhibition of cell proliferation and enhanced radiosensitivity in EBV-positive NPC patients by repressing of LMP1/JNKs/hypoxia-inducible factor 1 (HIF-1)/VEGF-mediated angiogenesis and supressing the LMP1/Akt-induced telomerase activity [174–177].