Our findings indicated that LFNG was highly expressed in higher stages of several cancers, including PAAD, LIHC, CHOL, and STAD, as well as in lung adenocarcinoma (LUAD), rectum adenocarcinoma (READ), esophageal carcinoma (ESCA), colon adenocarcinoma (COAD), breast invasive carcinoma (BRCA), kidney renal clear cell carcinoma (KIRC), testicular germ cell tumors (TGCT) and KIRP (Supplement Fig. 1). Here, LFNG is linked to colon adenocarcinoma.