In a Chinese cohort study, 192 patients with APS, 90 patients with seronegative APS (SN-APS), 193 patients with autoimmune diseases, and 120 healthy subjects were compared, and at least one NC-aPL was detected in 60.9% of SN-APS and 93.5% of APS patients [26]. The gene discussed is FASLG; the disease is autoimmune polyendocrinopathy.