HS6ST2 was highly expressed in bladder urothelial carcinoma (BLCA), cholangiocarcinoma (CHOL), pheochromocytoma and paraganglioma (PCPG), colon adenocarcinoma (COAD), esophageal carcinoma (ESCA), LUAD, thyroid carcinoma (THCA), and lung squamous cell carcinoma (LUSC). Here, HS6ST2 is linked to squamous cell lung carcinoma.