The data revealed a positive correlation of HS6ST2 with the detection of chemical stimuli in breast invasive carcinoma, lymphoid neoplasm diffuse large b-cell lymphoma, esophageal carcinoma, kidney renal clear cell carcinoma, liver hepatocellular carcinoma, sarcoma, stomach adenocarcinoma, kidney renal papillary cell carcinoma, and rectum adenocarcinoma, but the correlation was negative in lung squamous cell carcinoma. The gene discussed is HS6ST2; the disease is carcinoma of esophagus.