Positive associations were discovered between HS6ST2 and TET2 and DNMT3A in BLCA, prostate adenocarcinoma (PRAD), BRCA, head and neck squamous cell carcinoma (HNSC), THCA, and skin cutaneous melanoma (SKCM) when we calculated their expression levels with respect to other RNA methylation-related genes (Supplementary Table S1). Here, HS6ST2 is linked to head and neck squamous cell carcinoma.