In contrast, tumor tissues had lower levels of HS6ST2 than healthy tissues in breast invasive carcinoma (BRCA), kidney renal papillary cell carcinoma (KIRP), uterine corpus endometrial carcinoma (UCEC), kidney renal clear cell carcinoma (KIRC), and kidney chromophobe (KICH) (Fig. 1A). The gene discussed is HS6ST2; the disease is invasive breast carcinoma.