Through integrative analyses of TCGA data across 33 different tumor types, we found that ELFN1-AS1, the host lncRNA gene of SMIMP, exhibited a cancer-type specific expression pattern: ELFN1-AS1 had much higher expression in CRC, READ, ovarian cancer, stomach adenocarcinoma and esophageal cancer but very low expression in adrenocortical carcinoma, glioblastoma, renal cancer, low-grade glioma, pheochromocytoma and paraganglioma, sarcoma and thyroid cancer (Fig. 8a). Here, ELFN1 is linked to hereditary pheochromocytoma-paraganglioma.