Following two new loci were detected: TERC and KDM6B. The protective effect of chr14:TCL1A rs2887399_T was stronger in CPLDneg-CH, perhaps due to the differing effects of this allele in various CPLD mutation backgrounds (see CPLD gene specific CH GWAS associations, below). This evidence concerns the gene KDM6B and cyclic hematopoiesis.