RYR1 and hypertensive disorder: ABCA12, CLIP1, and NRAS were related to trabecular pattern (Supplementary Figures S3A, B, and C); ABCA4 and SLIT3 were related to insular pattern (Supplementary Fig. S3D and E); ABCA12, ATP13A3, and CLIP1 genes were related to the status of vascular invasion (Figs. 6B–D); INTS1 and RYR1 genes were related to the status of capsular invasion (Supplementary Figure S3F and G); and the SORL1 gene was related to the status of hypertension (Supplementary Figure S1H).