AKT1 and posterior cortical atrophy: In contrast, Selvaraj’s experiments showed that resveratrol (RSV) activated AMPK by inhibiting STIM1, which in turn downregulated the V-akt murine thymoma viral oncogene homolog (AKT)/mammalian target of rapamycin (mTOR) signaling axis and ultimately promoted autophagy in PCa cells [80].