IRF7 and COVID-19: From the previous searching results, we identified another two such AG-gain variants in intron-10 (last intron) of gene IRF7 (Fig. 6D): one heterozygous variant inside the high-risk region (VAR3: chr11-612805-C-T, c.1357-5G>A, MAF = 0 in gnomAD), which creates an AG 21-nt downstream from BP, in a patient with severe COVID-19 infection; the other heterozygous variant outside the high-risk region (VAR4: chr11-612820-G-T, c.1357-20C>A, MAF = 0 in gnomAD), which introduces an AG 6-nt downstream from BP, in a COVID-19 control individual (asymptomatic after COVID-19 infection).