The dysregulation of some angiogenic factors, such as vascular endothelial growth factor (VEGF), platelet-derived growth factor (PDGF), transforming growth factor-β (TGFβ), and basic fibroblast growth factor (bFGF), may be partially responsible for ovulation and aberrant cysts in PCOS (263). This evidence concerns the gene VEGFA and polycystic ovary syndrome.