DNMT3A and cyclic hematopoiesis: The most commonly mutated genes in clonal hematopoiesis (CH) are DNMT3A, TET2, ASXL1, PPM1D, JAK2, TP53, and SF3B1, which are also commonly mutated in AML, MDS, and myeloproliferative neoplasms (Jaiswal, 2020).