CD4 and urinary bladder cancer: Additionally, OAS1 can predict the efficacy of immunotherapy in bladder cancer patients, possibly because the expression of OAS1 is related to the infiltration of CD4+T cells, CD8+T cells, neutrophils, and dendritic cells in the tumor microenvironment of bladder cancer (43, 45).Our previous study revealed a significant association between OAS1 and the prognosis of pancreatic cancer (46).