AFP and hepatocellular carcinoma: The results has showed that: the level of AFP before treatment (HR 1.702, 95%CI 1.081-2.681, P = 0.022), giant HCC (HR 1.753, 95%CI 1.064-2.889, P = 0.028), PVTT type (HR 1.796, 95%CI 1.061-3.041, P = 0.029), extrahepatic metastasis (HR 2.105, 95%CI 1.240-3.572, P = 0.006), radiotherapy for PVTT (HR 0.231, 95%CI 0.133-0.401, P < 0.001), and the reduction of PVTT (HR 0.175, 95%CI 0.073-0.416, P < 0.001) were the independent influencing factors for PFS (Table 4).