It has been described that AML LICs downregulate NKG2DL expression, and show enhanced resistance to NK cell-mediated killing (44), however, we observed that after co-culture with NKG2D-CAR T cells, Exp-JKT had similar NKG2DL expression than Ctrl-JKT. The gene discussed is KLRK1; the disease is acute myeloid leukemia.