Cangma Huadu granules increased the abundance of Bifidobacterium, Parasutterella, Bacteroides, and Faecalibaculum in the intestine of mice at 7 days of PR8 infection, decreased the viral load and lung damage in the lungs, decreased TNF-a and IL-1β levels, and increased IL-10 levels (89). This evidence concerns the gene IL10 and infection.