CD1C and Cirrhosis: While the levels of classical monocytes (CD33+ CD14+ CD11b+ CD16-) were not altered, patients with cirrhosis, in particular those with decompensated disease, showed increased frequency of M-MDSC (CD33+CD14+CD11b+HLA-DRlow) along with reduced frequencies of both conventional dendritic cells type 1 (cDC1) (CD33+ CD14- HLA-DR+ CD141+ CD1c-) and type 2 (cDC2) (CD33+ CD14- HLA-DR+ CD141- CD1c+) (Figure 1).