Meanwhile, in CGGA301 GBM cohort, the top 5 gene sets were epithelial-mesenchymal transition (NES = 3.222), TNFA signaling via NFKB (NES = 3.190), interferon-gamma response (NES = 2.977), inflammatory response (NES = 2.970), and hypoxia (NES = 2.846) (Figure 5B). The gene discussed is TNF; the disease is glioblastoma.