These were; CVD (adjusted odds ratio (AOR): 2.45, 95% confidence interval (CI): 1.22–4.93, p = 0.01), tumor (AOR: 3.06, 95% confidence interval: 1.09–8.58, p = 0.03), baseline CD4+ T cell counts 50–199 cells/μl (AOR: 5.03, 95% confidence interval: 2.97–8.52, p < 0.001), and CD4+ T cells counts <50 cells/μl (AOR15.48, 95% CI:8.40–28.53, p < 0.001). Here, CD4 is linked to neoplasm.