AQP3 and rosacea: In addition, we performed KEGG pathway analysis and gene set enrichment analysis (GSEA) with each of the comparison group pairs and found that the NF-κB signaling pathway was the pathway most enriched in the WT (LL37) group, whereas NF-κB signaling pathway was not significantly enriched in group with AQP3 deficiency (Figure 3A-B), suggesting that this pathway might be involved in the AQP3-mediated inflammatory response in the context of rosacea.