TGFB1 and renal fibrosis: Besides, it is also reported that RUNX1 plays an important role in regulating renal fibrosis by promoting TGF-β induced renal tubular epithelial-to-mesenchymal transition (EMT) (Jakobczyk et al., 2022; Jeong et al., 2022; Li & Jia, 2022; Lin, 2022).