To explore the effect of TTC13 on tumor growth in vivo, we subcutaneously injected 786-0 cells transfected with either TTC13 NC or shRNA plasmid into nude mice and found that the tumor volume and weight of the shRNA group were evidently smaller than that of the NC group (Figs. 3A, 3B, 3C and 3D). This evidence concerns the gene TTC13 and neoplasm.