The neurodevelopmental disorder associated with GRIN2B (glutamate ionotropic receptor N-methyl-D-aspartate (NMDA) type subunit 2B) is caused by mutations of the gene called grin2b, which provides instructions to make a protein called GluN2B, which is found in neurons and is primarily expressed during pre-birth development. This evidence concerns the gene GRIN2B and neurodevelopmental disorder.