IGHE and urticaria: A number of studies showed allergic reactions to latex gloves, but it is also prudent here to mention that in study conducted by Gonzalo-Garijo et al. showed that acute reactions (contact urticaria, rhinoconjunctivitis, or both) were seen in their hospital's staff members who were earlier diagnosed with IgE-mediated hypersensitivity to latex and shown allergic to nitrile, but after using three lots of nitrile gloves, they were able to endure nitrile gloves from different lots made by similar or different manufacturers, and their count was also less than latex [14].