In the figure, epidermal growth factor receptor (EGFR), vascular endothelial growth factor A (VEGFA), mitogen-activated protein kinase 3 (MAPK3), signal transducer and activator of transcription 3 (STAT3) and prostaglandin-endoperoxide synthase 2 (PTGS2) were ranked high in degree value, indicating that they may play an important role in the process of anti-AD. Here, MAP4K3 is linked to Alzheimer disease.