In a mouse model of prostate cancer, YAP-TEAD induced expression of IL-6, colony-stimulating factors1-3, tumor necrosis factor-α, IL-3, C-X-C motif chemokine ligands1/2/5 and C-C motif chemokine ligand 2, and recruited myeloid-derived suppressor cells into the tumor microenvironment. This evidence concerns the gene IL6 and neoplasm.