The list was narrowed to ten hub genes, including GUCA2A, GUCA2B, GCG, SST, MS4A12, PLP1, CHGA, PYY, VIP, and CLCA4. However, just CLCA4 and MS4A12 expression levels had a statistically significant effect on CRC patients’ OS (63). This evidence concerns the gene CLCA4 and colorectal carcinoma.