(((GUCA2B[Title/Abstract]) OR (GUCY2C[Title/Abstract]) OR (GUCA2A[Title/Abstract]) OR (“guanylyl cyclase C”[Title/Abstract]) OR (“Guanylate cyclase”[Title/Abstract]) OR (“Gc-c receptor”[Title/Abstract]) OR (“guanylate”[Title/Abstract]) OR (“Guanylin”[Title/Abstract]) OR (“uroguanylin”[Title/Abstract])) AND ((Colorectal[Title/Abstract]) OR (intesti*[Title/Abstract]) OR (gastro*[Title/Abstract]) OR (colon[Title/Abstract])) AND ((cancer[Title/Abstract]) OR (malignan*[Title/Abstract]) OR (carcino*[Title/Abstract]) OR (neoplasm*[Title/Abstract]))). The gene discussed is GUCY2C; the disease is cancer.