Furthermore, LAG-3 expression was more prevalent in POLEmut and MMRd EC than in p53abn and p53wt EC in tumor cells (34.4% and 66.3% in POLEmut and MMRd versus 28.6% and 19.5% in p53abn and p53wt, P < 0.001). This evidence concerns the gene LAG3 and neoplasm.