In addition, four genes belonging to the first subgroup: DLG2, MTMR2, RBFOX1, and DCC, are involved in synapse formation and signal transduction (Lee et al., 2010; Alkallas et al., 2017; Wong et al., 2019; Prokopenko et al., 2022), what may indicate deregulation of these processes in the development of COVID-19 and AD-associated cognitive impairment. This evidence concerns the gene RBFOX1 and COVID-19.