PCBP1 and breast carcinoma: Additionally, NMuMG cells with loss of PCBP1 function gain stemness potential and differentiation potency, as demonstrated by full reconstruction of the mouse mammary gland following injection into surgically cleared fat pads.7 The PCBP1-driven characteristics of disease in our mouse model demonstrate that EMT manifests in neoplastic cells that exemplify the characteristics of breast cancer stem cells (BCSCs).7,11