NT-proBNP concentrations were shown to inversely correlate with the parameters of left ventricular diastolic function, such as the volume of the left atrium and E/A, in patients with liver cirrhosis and chronic liver disease, but due to low specificity, did not prove useful in screening of patients with cirrhotic cardiomyopathy (40,69,72,74). The gene discussed is NPPB; the disease is cirrhosis of liver.