MYL9 and colorectal carcinoma: To study the biological effect of MYL9 gene silencing in CAFs on CRC, we used a lentivirus to steadily knockdown the MYL9 gene in CAFs, CAFs with or without MYL9 gene knockdown and LoVo cells were injected subcutaneously and intravenously at a ratio of 1:1 to induce tumorigenesis and metastasis in nude mice.