KIF5A and Autosomal dominant spastic paraplegia type 10: When we looked at the clinical consistency between the triggering case and its associated ORPHAcode, the KIF5A-related triggering case showed very good clinical consistency with the HPO annotations of the corresponding ORPHAcode Autosomal dominant spastic paraplegia type 10 (ORPHA:100991) [37], subsequently confirmed by the clinician.