To investigate whether m6A modification contributes to the oncogenic roles of AC026356.1 in HCC, we knocked down WTAP and METTL16 in AC026356.1 overexpressed and control HCCLM3 cells, which extremely reduced the m6A modification level of AC026356.1 (Fig. 5A,B). Here, METTL16 is linked to hepatocellular carcinoma.