ALK and anaplastic large cell lymphoma: However, in a study comparing three prognostic indices (IPI, PIT, and NCCN-IPI) in patients with ALCL without anaplastic large-cell lymphoma kinase (ALK) (n = 152), AITL (n = 145) and PTCL-NOS (n = 306), NCCN-IPI appeared to separate prognostic groups, although this difference did not result in markedly better c-statistics13.