COL5A1 and neoplasm: Similarly, in esophageal carcinoma [41, 42, 44, 45], BBOX1-AS1 interacts with three miRNAs (miR-506-5p, miR-513a-3p, miR-361-3p) and subsequently upregulates the expression of four target genes (EIF5A, SLC7A11, COL5A1, COL1A1), promoting tumor cell growth, migration, invasion, and accelerating the progression and metastasis of esophageal cancer.