Similarly, in esophageal carcinoma [41, 42, 44, 45], BBOX1-AS1 interacts with three miRNAs (miR-506-5p, miR-513a-3p, miR-361-3p) and subsequently upregulates the expression of four target genes (EIF5A, SLC7A11, COL5A1, COL1A1), promoting tumor cell growth, migration, invasion, and accelerating the progression and metastasis of esophageal cancer. The gene discussed is BBOX1; the disease is neoplasm.