Investigations while asymptomatic at the time of diagnosis showed mild lactic acidosis 2 mmol/L (Ref range: 0.5–1.6 mmol/L) and the liver function tests showed elevated ALT and AST at 425 U/L (Ref range: 7–56 U/L) and 70 U/L (Ref range 0–35) respectively. This evidence concerns the gene GPT and lactic acidosis.