KDM6A and renal pelvis/ureter urothelial carcinoma: Compared with normal urothelial samples, the expression level of KDM6A in UTUC specimens was shown to be significantly reduced, while low KDM6A expression was associated significantly with higher tumor grade, shorter cancer-specific and disease-free survival time, suggesting that low expression and downregulation of KDM6A may accelerate the progression of UTUC [41].