ATP2A2 and infection: However, when exploring our data, we also found that canonical genes associated with thermogenesis, such as Ucp126, were downregulated in infected males and females (Supplementary Data 2 and 3), Moreover, expression of genes associated with UCP1-independent thermogenesis, including Atp2a1, Atp2a2, and Atp2a327 were not altered during infection (Supplementary Data 2 and 3), suggesting that thermogenesis is not activated in this context.