To explore the relationship of BCR/TCR characteristics, TILs and prognosis with the tumor microenvironment composition in the NeoALTTO and CALGB 40601 cohorts, we applied the microenvironment cell populations (MCP)-counter tool37, which allows to estimate the abundance scores of different immune and stromal cells (Supplementary data 15, 16). This evidence concerns the gene BCR and neoplasm.