To further investigate the association between normal UACR and outcome events, we conducted subgroup analyses stratified by sex, age, race, treatment group, CVD history, heart failure, previous hyperlipidemia, previous hypertension, duration of diabetes, BMI, HbA1c, eGFR, and insulin use in Fig. 5 and elsewhere (18). The gene discussed is INS; the disease is hyperlipidemia.