In total IBD cohort, there was a significant negative correlation between MCP-1 and calprotectin (r = -0.388, P<0.01), a positive association of TNF-a with CRP (r = 0.318, P<0.01) and of G-CSF with PUCAI (r = 0.465, P<0.04). Here, CRP is linked to inflammatory bowel disease.