EIF2AK3 and myocardial infarction: We noted 2.5- to 10-fold increases in protein levels of GRP78, ATF6, and activated/phosphorylated PERK (P-PERK) in ischemic hearts (Fig. 1; P < 0.01 or 0.05 vs. sham-MI by 2-tailed heteroscedastic t test).