In contrast, E-cadherin was significantly upregulated in response to MTSS1 expression in both 5-8F and TW03 NPC cells in line with the qPCR data (Supplementary Figure S3A), while other adherens junction components, such as Catenin alpha-1 (CTNNA1) and Occludin (OCLN) were downregulated by MTSS1 in 5-8F but not in TW03 (Supplementary Figure S3A). This evidence concerns the gene CDH1 and nasopharyngeal carcinoma.