Subsequent investigations suggested that further rearrangements involving der (15)t (12; 15) or der (12)t (12; 15) in CFS might lead to a suppression of ETV6-NTRK3 molecular expression, potentially indicating the relatively benign nature of the tumor (Punnett et al., 2000) (Figure 3). Here, ETV6 is linked to myalgic encephalomeyelitis/chronic fatigue syndrome.