The oltipraz pretreatment could significantly inhibited the TGF-β1 caused increase of these inflammatory factors in the supernatants of HFLS (p < 0.01 vs. TGF-β1 induction group), and the effects of oltipraz could be significantly reversed by Lv-TRAP-1 infection (p < 0.01 vs. oltipraz pretreatment + TGF-β1 induction group) (Fig. 4-B). This evidence concerns the gene TGFB1 and infection.