Albright’s Hereditary Osteodystrophy (AHO) is a condition caused by mutations in the GNAS gene, characterized by various physical traits, including short stature, brachydactyly, obesity, a round face, cognitive impairment, and the abnormal formation of bone outside the skeletal system, referred to as heterotopic ossification (48, 49). The gene discussed is GNAS; the disease is Cognitive impairment.