Stenosis, lean body mass, reduced suckling, weakness and inactivity, growth retardation, high postpartum mortality, decreased blood glucose levels, low pancreatic hyperglycemic concentrations, increased glucose tolerance and insulin sensitivity, reduced adipose tissue, hyperphosphatemia, hypocalcemia, increased serum concentrations of PTH and 1,25-dihydroxy vitamin D, decreased abundance of the sodium-phosphate cotransporter Npt2a in renal brush membranes, and slightly increased PTH-induced urinary excretion of cAMP. Here, INS is linked to hyperphosphatemia.