AG administration promoted cell apoptosis and attenuated cell proliferation by up-regulating PARP and Bim and down-regulating Bcl-2, p-PI3K, and p-AKT (Wang et al., 2021), indicating that activating PI3K/AKT signaling is a promising mechanism of AG in preventing gastric cancer. The gene discussed is AKT1; the disease is gastric cancer.