CXCL8 and allergic disease: Similarly, it inhibits the expression of IL-8 in the cystic fibrosis bronchial epithelial IB3-1 cell line (Borgatti et al., 2011), and inhibits the expression of IL-4 in RBL-2H3 cells, which are commonly used in immunological experiments, inflammation and allergy (Kim H. et al., 2021).