TIM-3 expression has also been found to correlate to poor prognosis in other hematologic malignancies such as DLBCL, ALL, MDS, Chronic Myelogenous Leukemia (CML), and Chronic Myelomonocytic Leukemia (CMML) (112–115). The gene discussed is HAVCR2; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.